Scientists have created a smart ‘band-aid’ that uses electrical currents to heal wounds 25% faster than traditional methods by stimulating tissue to speed up recovery.
The smart bandage is made up of wireless circuitry that uses the flow of electrical currents and temperature sensors to monitor wound healing progress.
The high-tech device promotes faster wound closure, increases new blood flow to injured tissue, and improves skin recovery by significantly reducing scar formation, researchers say.
The high-tech wireless bandage is the work of Stanford University researchers and was featured in a paper published Nov. 24 in Nature Biotechnology.
Scientists have developed a smart dressing that can help speed up wound healing by monitoring the wound and treating it at the same time
The smart bandage is made up of wireless circuitry (above) that uses the flow of electrical currents and temperature sensors to monitor wound healing progress
When a person’s wound is not yet healed or the dressing detects an infection, the sensors can apply more electrical stimulation to the wound area to speed tissue recovery and reduce infection.
The Smart Bandage’s biosensors can track biophysical changes in the local environment and provide a real-time, fast and highly accurate means of measuring wound status.
Researchers were able to track real-time sensor data on a smartphone without the need for wires.
“In mice, we demonstrate that our wound care system can continuously monitor skin impedance and temperature and deliver electrical stimulation in response to the wound environment,” the study abstract states. researchers.
In preclinical wound models with mice, the treatment group healed about 25% faster than the control group.
“By sealing the wound, the smart bandage protects while healing,” Yuanwen Jiang, study co-first author and post-doctoral researcher at the Stanford School of Engineering, said in a statement.
“But it’s not a passive tool. It is an active healing device that could transform the standard of care in the treatment of chronic wounds.
The Smart Bandage’s biosensors can track biophysical changes in the local environment and provide a real-time, fast, and highly accurate means of measuring wound status.
The scientists also warned that the smart bandage is currently a proof of concept and there are some challenges
Scientists wanted to determine why and how electrical stimulation promotes wound healing.
They now believe that electrical stimulation promotes the activation of pro-regenerative genes such as Selenop, an anti-inflammatory gene that helps eliminate pathogens and repair wounds, as well as Apoe, which has been shown to it increases muscles and soft muscles. tissue growth.
Additionally, electrical stimulation increased the amount of white blood cell populations, particularly monocytes and macrophages, which may also play a role in certain phases of wound healing.
“With stimulation and sensing in one device, the smart bandage not only speeds up healing, but it also tracks wound improvement,” Artem Trotsyuk, also the study’s co-first author and currently chair of the department of surgery and professor of biomedical engineering at the University of Arizona in Tucson, explained.
The scientists also warned that the smart bandage is currently a proof of concept and there are some challenges.
These obstacles include increasing the size of the human-scale device, reducing costs, and addressing long-term data storage issues.
All of these issues should be resolved before going into mass production.
They also noted other potential sensors that could be added to the device, including those that measure metabolites and other biomarkers.
A potential barrier to clinical use would be “hydrogel rejection”, whereby a person’s skin may react to the device and create an improper gel-skin combination.
The researchers also noted other potential sensors that could be added to the device, including those that measure metabolites and other biomarkers.
. scientists create BANDAGE intelligent that can heal wounds quickly thanks to electrical stimulation to sensors